The objectives of this course are
– to apply quantum chemical principles to organic reactions
– to gain a detailed understanding of reaction mechanisms (fundamentals)
– to learn about tools to decipher reaction mechanisms
– broaden the scope of reactivity for advanced organic synthesis with a focus on orbital symmetry-controlled reactions
Schedule of the Lecture:
| Introduction and Review of Concepts | ||
| Conformational Analysis I | ||
| Conformational Analysis II | ||
| Diastereoselective Reactions and Ring Closures | ||
| Thermochemistry | ||
| Kinetics | ||
| Tools to decipher reaction mechanisms | ||
| Molecular Orbital Theory | (+ endriandric acid C) | |
| Aromaticity and Anti-aromaticity / Annulenes (I) | ||
| Aromaticity and Anti-aromaticity / Annulenes (II) | ||
| Pericyclic Reactions / Theory | ||
| Cycloadditions & Cycloreversions | ||
| Electrocyclizations and Retro-Electrocyclizations | ||
| Sigmatropic Shifts | ||
| Rearrangements and Cheletropic Reactions | ||
- Course owner: Dr. Oliver Dumele
Semester: WiTerm 2022/23